I just bumped into size limit of a method in a cfc. Since the methods get turned into java classes, they are limited in size to 65535 characters. Before you get all nuts telling me "DOOD! Your methods shouldn't be that big", relax. It was just a bunch of database calls that happen sequentially. There's no real complexity in there, only tedium.
Lucky for me, it's pretty easy to break it up into a bunch of small private methods. Just for reference, you'll hit the limit somewhere around 900 lines of fairly dense code. If things start looking that big, it's time to start rethinking the structure.